rofessor, Department of Histology and Embryology, College of Veterinary Medicine

Supervisor of both master and Ph.D students

Dr. Su received his Ph.D degree from College of Veterinary Medicine, Northeast Agricultural University in 2010. From 2011 to 2016, he finished his Postdoctoral training in College of Human Medicine, Michigan State University, USA. Dr. Su`s research interest is development, physiology and pathology of female reproduction, specifically endometrium. He has published his research on peer-reviewed journals such as PNAS and JCEM.

Uterus is the unique organ in female mammals that supports embryo and fetal development by providing a suitable environment and nutrition supplies. Understanding the processes of uterine development, physiology and pathology can improve not only human IVF clinic but also the efficiency of animal production.

Currently, Dr. Su is focusing his research on role of Notch Signaling in embryo implantation, decidualization, uterine adenogenesis, and postpartum repair of endometrium, using methods including cell culture, gene engineering mouse model, and other cellular and molecular technologies. 

Education and Training:

2011.8 to 2016.10 Postdoctoral Fellow, College of Human Medicine, Michigan State University, Grand Rapids, MI, USA;

2012.4 to 2012.6 Frontiers in Reproduction (FIR), Marine Biological Laboratory, Woods Hole, MA, USA;

2005.9 to 2010.6 Ph.D in Basic Veterinary Medicine, College of Veterinary Medicine, Northeast Agricultural University, Harbin, China;

2001.9 to 2005.6 B.S., College of Life Science, Northeast Agricultural University, Harbin, China.

Funding:

1.Effects of Notch Signaling Pathway on Mouse Uterine Adenogenesis and Development. General Program, National Natural Science Foundation of China, 31771664, ¥600,000.00, 2018-2021, Principal investigator

2.Scientific Research Foundation, South China Agricultural University, ¥1,000,000.00, 2016-2021, Principal investigator

3.Scientific Research Foundation, College of Veterinary Medicine, ¥200,000.00, 2017-2020, Principal investigator

Selective Publications: (* First Author, #Corresponding Author)

1.Strug MR*, Su RW*, Kim TH, Mauriello A, Ticconi C, Lessey BA, Young SL, Lim JM, Jeong JW, Fazleabas AT#. RBPJ-κapa mediates uterine repair in the mouse and is reduced in women with recurrent pregnancy loss. FASEB J. 2018; 32(5):2452-66.

2.Strug MR*, Su RW, Young JE, Dodds WG, Shavell VI, Díaz-Gimeno P, Ruíz-Alonso M, Simón C, Lessey BA, Leach RE, Fazleabas AT. Intrauterine human chorionic gonadotropin infusion in oocyte donors promotes endometrial synchrony and induction of early decidual markers for stromal survival: a randomized clinical trial. Human Reproduction. 2016; 31(7):1552-61.

3.Su RW*, Strug MR, Miele L, Jeong JW, Fazleabas AT#. Aberrant activation of canonical Notch1 signaling in the mouse uterus decreases progesterone receptor by hypermethylation and leads to infertility.Proc Natl Acad Sci USA. 2016; Feb 23;113(8):2300-5.

4.Su RW*#, Fazleabas AT#. Implantation and Establishment of Pregnancy in Human and non-human Primates. Chapter 10 in “Regulation of Implantation and Establishment of Pregnancy in Mammals” Eds. Geisert RD and Bazer FW. ISBN: 978-3-319-15855-6. Adv Anat Embryol Cell Biol.2015; 216:189-213.

5.Su RW*, Strug MR, Joshi NR, Jeong JW, Miele L, Lessey BA, Young SL, Fazleabas AT#. Decreased Notch pathway signaling in the endometrium of women with endometriosis impairs decidualization. J Clin Endocrinol Metab.2015; 100(3):E433-42.