Discipline: Preventive Veterinary Medicine Tel\Fax: 020-85283309 E-Mail: qiwenbao @scau.edu.cn Address: College of Veterinary Medicine, South China Agricultural University, 510642 Additional Information: Department of Preventive Medicine
Resume:
Wenbao Qi,Male,Born in Shandong province, Ph.D. in Agriculture, Professor. He received his Ph.D Degree in 2007 at South China Agricultural University. Focusing on animal influenza viruses (AIV) and Japanese Encephalitis Viruses(JEV). He has published more than 20 SCI papers including on Journal of Virology, Eurosurveillance and BMC Medicine etc. In the past 5 years, two H5 subtype vaccines have been approved.
Education and Training Program:
2004.9-2007.7: PhD candidate, National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences(CAAS)
College of Veterinary Medicine, SCAU
Thesis topic: Inhibition of Japanese Encephalitis Virus Replication by RNA Interference and Study on the Function of JEV Untranslated Region
Supervisor: Prof. Guangzhi Tong (CAAS), Prof. Ming Liao (SCAU)
2001.9-2004.7: Master of Science, College of Veterinary Medicine, SCAU
Thesis topic: Study and application of Real Time PCR Method of Bovine Tuberculosis
Supervisor: Prof. Manlin Luo
1997.9-2001.7: Bachelor of Science, Qingdao Agricultural University
Major: Veterinary Science
Working Experience:
2015.12- Present Professor, Director of Department of Animal Infectious Diseases, College of Veterinary Medicine, SCAU
2009.9- 2015.12 Associate professor, Associated Director of Department of Animal Infectious Diseases, College of Veterinary Medicine, SCAU
2007.7- 2010.12 Assistant professor, Department of Animal Infectious Diseases, College of Veterinary Medicine, SCAU
Research Interests:
(1) The molecular basis of the host range and virulence by reverse genetics, (2) New vaccines of avian influenza viruses(AIV), (3) The evolution of AIVs, (4) Virus protein and host interaction.
Grants:
National Natural Science Foundation of China (31672586), Natural Science Foundation of Guangdong Province (2015A030313422) ,“Special Support Plan of Guangdong Province in Science and Technology for Talents (2014TQ01N198).”
Publications:
1.Qi W, Zhou X, Shi W, Huang L, Xia W, Liu D, Li H, Chen S, Lei F, Cao L, Wu J, He F, Song W, Li Q, Li H, Liao M, Liu M.Genesis of the novel human-infecting influenza A(H10N8) virus and potential genetic diversity of the virus in poultry, China. Euro Surveill. 2014 Jun 26;19(25). pii: 20841.(IF=7.2)
2.Qi W, Su S, Xiao C, Zhou P, Li H, Ke C, Gray GC, Zhang G, Liao M. Antibodies against H10N8 avian influenza virus among animal workers in Guangdong Province before November 30, 2013, when the first human H10N8 case was recognized. BMC Med. 2014 Oct 27;12:205. (IF=7.9)
3.Xiao C, Ma W, Sun N, Huang L, Li Y, Zeng Z, Wen Y, Zhang Z, Li H, Li Q, Yu Y, Zheng Y, Liu S, Hu P, Zhang X, Ning Z, Qi W, Liao M. PB2-588 V promotes the mammalian adaptation of H10N8, H7N9 and H9N2 avian influenza viruses. Sci Rep. 2016 Jan 19;6:19474. (IF=4.3)
4.Qi W, Tian J, Su S, Huang L, Li H, Liao M. Identification of potential virulence determinants associated H9N2 avian influenza virus PB2 E627K mutation by comparative proteomics. Proteomics. 2015 May;15(9):1512-24. (IF=4.0)
5.Qi W, Shi W, Li W, Huang L, Li H, Wu Y, Yan J, Jiao P, Zhu B, Ma J, Gao GF, Liao M, Liu D. Continuous reassortments with local chicken H9N2 virus underlie the human-infecting influenza A (H7N9) virus in the new influenza season, Guangdong, China. Protein Cell. 2014 Nov;5(11):878-82. (IF=5.4)
6.Su S, Qi W, Zhou P, Xiao C, Yan Z, Cui J, Jia K, Zhang G, Gray GC, Liao M, Li S. First evidence of H10N8 Avian influenza virus infections among feral dogs in live poultry markets in Guangdong province, China. Clin Infect Dis. 2014 Sep 1;59(5):748-50. (IF=8.2)
7.Qi W, Tian J, Zhang C, He J, Ning Z, Jiao P, Liao M. Potential role of HPA axis and sympathetic nervous responses in depletion of B cells induced by H9N2 avian influenza virus infection. PLoS One. 2012;7(12):e51029. (IF=2.8)
8.Su S, Qi W, Chen J, Zhu W, Huang Z, Xie J, Zhang G. Seroepidemiological evidence of avian influenza A virus transmission to pigs in southern China. J Clin Microbiol. 2013 Feb;51(2):601-2. (IF=3.7)
9.Li X, Qi W, He J, Ning Z, Hu Y, Tian J, Jiao P, Xu C, Chen J, Richt J, Ma W, Liao M. Molecular basis of efficient replication and pathogenicity of H9N2 avian influenza viruses in mice. PLoS One. 2012;7(6):e40118. (IF=2.8)
10.Tian J, Qi W, Li X, He J, Jiao P, Zhang C, Liu G, Liao M. A single E627K mutation in the PB2 protein of H9N2 avian influenza virus increases virulence by inducing higher glucocorticoids (GCs) level. PLoS One. 2012;7(6):e38233. (IF=2.8)
11.He J, Qi W, Wang L, Tian J, Jiao P, Liu G, Ye W, Liao M. Amaryllidaceae alkaloids inhibit nuclear-to-cytoplasmic export of ribonucleoprotein (RNP) complex of highly pathogenic avian influenza virus H5N1. Influenza Other Respir Viruses. 2013 Nov;7(6):922-31. (IF=2.7)
12.Su S, Qi W, Chen J, Cao N, Zhu W, Yuan L, Wang H, Zhang G. Complete genome sequence of an avian-like H4N8 swine influenza virus discovered in southern China. J Virol. 2012 Sep;86(17):9542. (IF=4.7)
13.Yu M, Qi W, Huang Z, Zhang K, Ye J, Liu R, Wang H, Ma Y, Liao M, Ning Z.Expression profile and histological distribution of IFITM1 and IFITM3 during H9N2 avian influenza virus infection in BALB/c mice. Med Microbiol Immunol. 2015 Aug;204(4):505-14. (IF=3.1)
14.Yu Y, Zhang Z, Li H, Wang X, Li B, Ren X, Zeng Z, Zhang X, Liu S, Hu P, Qi W, Liao M. Biological Characterizations and Functions of Clade 2.3.4.4 H5 AvianInfluenza Viruses (H5Nx) Embodying Different Neuraminidases. Frontiers in Microbiology. 2017 Jun 14;8:1084. (IF=4.1)
15.Hu P, Chen X, Huang L, Liu S, Zang F, Xing J,Zhang Y, Liang J, Zhang G, Liao M, Qi W. A highly pathogenic porcine reproductive and respiratory syndrome virus candidate vaccine based on Japanese encephalitis virus replicon system. Peer J. 2017 Jul 20;5:e3514. (IF=2.2)
16.Qi W, Jia W, Liu D, Li J, Bi Y, Xie S, Li B, Hu T, Du Y, Xing L, Zhang J, Zhang F, Wei X, Eden JS, Li L, Tian H, LiW, Su G, Lao G, Xu C, Xu B, Liu W, Zhang G, Tao Ren T, Holmes ED, Cui J, Shi W, Gao GF, LiaoM. Emergence and adaptation of a novel highly pathogenic H7N9 avian influenza virus in birds and humans from a 2013-human-infecting low pathogenic ancestor. J Virol.2017 Oct 25. pii: JVI.00921-17.(IF=4.7)
17.Zhang J, Lao G, Zhang R, Wei Z, Wang H, Su G, Shan N, Li B, Li H, Yu Y, Jia W, Liao M, Qi W.Genetic diversity and dissemination pathways of highly pathogenic H5N6 avian influenza viruses from birds in southwestern China along the East Asian-Australian migration flyway. J Infect. 2017 Dec 12. pii: S0163-4453(17)30382-1.