Hongxia Jiang, Ph.D.

Professor of Basic Veterinary Medicine, National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria (deputy director); College of Veterinary Medicine, South China Agricultural University (SCAU)

Curriculum Vitae:

Education:

1999-2002 PhD in Agriculture, South China Agricultural University, China

1996-1999 MS in Agriculture, South China Agricultural University, China

1987-1991 BA in Veterinary Medicine, Tarium Agricultural University, China

Professional Experience:

2009-2010   Academic visitor, Institute of Microbiology and Infection, University of Birmingham, British

2002-present  Professor, National Risk Assessment Laboratory for Antimicrobial Resistance of Animal Original Bacteria; College of Veterinary Medicine, South China Agricultural University, China.

1991-1996  Lecturer, College of Veterinary Medicine, Tarim University, Xinjiang, China

Research Interest:

My work focuses on antimicrobial resistance particular in animal original Salmonella and Escherichia coli. In China resistance in bacteria is getting worse and worse, not only compromising the effect of antimicrobials, but also posing threat to human and public health. My specific interests relate to understanding the evolution of antibiotic resistance, transmission routes of resistance, as well as the study of membrane proteins in terms of resistance, e.g. multidrug efflux pump (AcrAB-TolC) in fluoroquinolone-resistant Salmonella and E. coli.

SCI Publication in recent 5 years (* indicates corresponding authors):

1.Chuan-Zhen Zhang, Si-Qi Ren, Man-Xia Chang, Pin-Xian Chen, Hong-Xia Jiang*.Resistance mechanism and fitness of Salmonella Typhimurium and Salmonella Enteritidis during the evolution of resistance under selective pressure with ciprofloxacin in vitro. Scientific Reports. 2017 Aug 22;7(1):9113. doi: 10.1038/s41598-017-09151-y.

2.Chuan-Zhen Zhang, Lei Yang, Pin-Xian Chen, Hong-Xia Jiang*. Coordinated expression of AcrAB-TolC and eight other functional efflux pumps through co-regulation of ramA and marA when any of them are impaired in Salmonella enterica serovar Typhimurium. Microbial Drug Resistance. 2017 Jun 26. doi: 10.1089/mdr.2017.0086.

3.Chuan-Zhen Zhang, Man-Xia Chang, Lei Yang, Yan-Yan Liu, Pin-Xian Chen, Hong-Xia Jiang*. Up-regulation of AcrEF in quinolone resistance development in E. coli when AcrAB-TolC function is impaired. Microbial Drug Resistance. 2017 May 18. doi:10.1089/mdr.2016.0207.

4.Wen-Hui Zhang, Chuan-Zhen Zhang, Zhi-Jie Liu, Xi-Xi Gu, Wan Li, Ling Yang, Ya-Hong Liu, Zhen-Ling Zeng, Hong-Xia Jiang*. In Vitro Development of ciprofloxacin resistance of Salmonella enterica serovars Typhimurium, Enteritidis and Indiana isolates from foodanimals. Microbial Drug Resistance. 2017 Jan 13. doi: 10.1089/mdr.2016.0119

5.Nan Zhang, Xiaomei Ye, Yuzhi Wu, Zilong Huang, Xiaoyan Gu, Qinren Cai, Xiangguang Shen, Hongxia Jiang, Huanzhong Ding. Evaluation of the killing of Mycoplasma gallisepticum by danofloxacin, doxycycline, tilmicosin, tylvalosin and valnemulin. PLoS One. 2017 Jan 4;12(1):e0169134.

6.Ling Yang, Wan Li, Gui-Ze Jiang, Wen-Hui Zhang, Huan-Zhong Ding, Ya-Hong Liu, ZhenLing Zeng* and Hong-Xia Jiang*. Characterization of a P1-like bacteriophage carrying CTX-M-27 in Salmonella spp. resistant to third generation cephalosporins isolated from pork in China. Scientific Reports. 2017 Jan 18;7:40710. doi: 10.1038/srep40710.

7.Nan Zhang, Xiaoyan Gu, Xiaomei Ye, Xun Wu, Bingxu Zhang, Longfei Zhang, Xiangguang Shen, Hongxia Jiang and Huanzhong Ding. The PK/PD Interactions of doxycycline against Mycoplasma gallisepticum. Frontiers in Microbiology. 2016 May 4;7:653.

8.Wen-Hui Zhang, Xiang-Yan Lin, Liang Xu, Xi-Xi Gu, Ling Yang, Wan Li, Si-Qi Ren, Ya-Hong Liu, Zhen-Ling Zeng and Hong-Xia Jiang*. CTX-M-27 producing Salmonella enterica serotypes Typhimurium and Indiana are prevalent among food-producing animals in China. Frontiers in Microbiology, 2016 Mar 31;7:436

9.Xiao-Ping Liao, Jing Xia, Lei Yang, Liang Li, Jian Sun, Ya-Hong Liu and Hong-Xia Jiang*. Characterization of CTX-M-14-producing Escherichia coli from food-producing animals. Frontiers in Microbiology, 2015 Oct 15;6:1136

10.Wen-Hui Zhang, Si-Qi Ren, Wan Li, Xi-Xi Gu, Ling Yang, Zhen-Ling Zeng, Ya-Hong Liu, and Hong-Xia Jiang*. High frequency of virulence genes among Escherichia coli with the blaCTX-M genotype from diarrheic piglets in China. Veterinary Microbiology，180 (2015) 260–267。

11.Ling Yang, Lei Yang, Dian-Hong Lü , Wen-Hui Zhang, Si-Qi Ren, Ya-Hong Liu, Zhen-Ling Zeng, Hong-Xia Jiang*. Co-prevalance of PMQR and 16S rRNA methylase genes in clinical Escherichia coli isolates with high diversity of CTX-M from diseased farmed pigeons. Veterinary Microbiology 178 (2015) 238–245.

12.Guo YF, Zhang WH, Ren SQ, Yang L, Lü DH, Zeng ZL, Liu YH, Jiang HX*. IncA/C PlasmidMediated Spread of CMY-2 in Multidrug-resistant Escherichia coli from food animals in China. PLoS One. 2014 May 9;9(5):e96738.

13.Jiang HX, Li S, Liu J, Zhang X-H, RenYN, Zhang WH, Zhang JY, Liu YH, Webber MA, D OO, Zeng ZL, Piddock LJV. Multiple transmissible genes encoding fluoroquinolone and thirdgeneration cephalosporin resistance co-located in non-typhoidal Salmonella isolated from food-producing animals in China. International Journal of Antimicrobial Agents. 2014 Mar; 43(3):242-7. 

Contact:

College of Veterinary Medicine, South China Agricultural University, Guangzhou, 510642, China

+86-20-8528-3934 (O)

Fax: +86-20-8528-4896

E-mail: hxjiang@scau.edu.cn